Cancer antigen 125 (CA 125, a protein found on many ovarian cancer cell surfaces) is the most investigated biomarker that may be effective in the diagnosis of endometriosis. A meta-analysis was published recently in BJOG: An International Journal of Obstetrics and Gynaecology that included 22 studies with 3626 participants. Fourteen studies with 2920 participants were meta-analysed for the sensitivity and specificity of >30 units/ml CA 125 in the diagnosis of endometriosis. Individual study sensitivities ranged from 0% to 87% and specificity from 51% to 100%. The pooled sensitivity of >30 units/ml CA 125 was 52.4%, while the specificity was 92.7%. this posthttp://foresthillmotel.com/moremichaelsimmons/2016/08/05/he-or-she-should-be-able-to-influence-their-emotions-their-thoughts-and-even-their-actions-with-the-words-they-speakFurthermore, the sensitivity of CA 125 was higher with a more severe disease. It seems that a positive result means endometriosis, but a negative one might not mean the absence of the disease. In conclusion, CA 125 is a highly specific diagnostic method for endometriosis. However, a <30 units/ml CA 125 result does not mean that there is no endometriosis and further investigation is needed to find biomarkers that are able to diagnose endometriosis with a higher sensitivity. Written By: Dr.
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“Visualization tools are essential to the future of garment design and AccuMark 3D is helping pave the way forward whether using traditional or 3D printed textiles.” Danit’s latest innovation was a custom dress for the Paralympics, for more information read her interview with Elizabeth King on the experience. http://www.gerbertechnology.com/news/danit-peleg-on-her-latest-innovations-in-3d-printed-garments/ . When creating this custom dress, Danit worked closely with Gerber’s AccuMark 3D team to design and visualize the dress prior to printing the various pieces. The process ensured the dress would perform as well as the dancer while on stage. The result of using AccuMark 3D for design and visualization allowed Peleg to understand the garment dynamics without spending hundreds of hours creating samples. AccuMark 3D visualization, animation and simulation technology is part of the AccuMark family of products. AccuMark 3D presents realistic modeling of fabric properties allowing designers to visualize their designs before costly samples are created. This allows for a decrease in sample costs by 75 percent or more. Peleg is currently working on her next line of garments utilizing YuniquePLM In The Cloud to manage her data from concept to creation and beyond. She states, “Having all my data in one central system allows me to spend more time designing and less time managing all the data for the new line.” In the future, Danit and the AccuMark 3D team will collaborate by using the software to send patterns in the form of 3D print files directly to the printer similar to the current integration with digital fabric printing. About Danit Peleg Peleg created her first 3D-printed collection as part of her graduate collection for her fashion design degree at Shenkar College of Engineering and Design. The collection was created using home printers following nine months of research and development.
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