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The trial demonstrated that adding Praluent to existing therapy reduced LDL cholesterol by approximately 50% from baseline (compared to 2% increase for placebo). Praluent significantly reduced the need for apheresis treatment by 75% compared to placebo (p less than 0.0001), the primary endpoint of the study. Results will be presented today at a Hot Line session at the ESC Congress 2016 in Rome, Italy. interview skills powerpoint high schoolApheresis is a procedure similar to kidney dialysis where bad ( LDL ) cholesterol is removed from the blood, and is usually reserved for high-risk patients with very high cholesterol unable to achieve their cholesterol-lowering goals on any other therapy. Despite being treated with apheresis and entering ODYSSEY ESCAPE with very high LDL cholesterol levels (4.7 millimoles/liter [mmol/L] or 181 milligrams/deciliter [mg/dL]), nearly two-thirds (63%) of patients treated with Praluent no longer required apheresis therapy after six weeks of receiving Praluent. At this same time point, the average LDL cholesterol level among the Praluent-treated group was 2.3 mmol/L (90 mg/dL), compared to 4.8 mmol/L (185 mg/dL) in the placebo group. 2:52 am Amgen presents new data for Repatha indicating efficacy and safety across risk groups ( AMGN ) : Coannounced data presented showing Repatha consistently reduced low-density lipoprotein cholesterol (LDL-C) in patients across cardiovascular (:CV) risk subgroups or with familial hypercholesterolemia. The analysis showed that treatment with Repatha 140 mg every two weeks or 420 mg monthly consistently reduced levels of LDL-C and other lipids from baseline to the mean of weeks 10 and 12 across all risk categories compared to placebo or ezetimibe controls. For example, among very high-risk patients, Repatha reduced LDL-C levels from baseline 65.2% more than placebo and 40.7% more than ezetimibe.
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You should always ensure that you have letters of reference that are updated and ready to use. Many people are saying that they’re ready with their references, but it’s a great idea to have the letters on hand. This keep the interviewer from having to do phone tag for references, and they can easily read them to see that you’re a great candidate.